Methyl 3-cyano-1H-indole-4-carboxylate - Names and Identifiers
Methyl 3-cyano-1H-indole-4-carboxylate - Physico-chemical Properties
Molecular Formula | C11H8N2O2
|
Molar Mass | 200.19 |
Density | 1.33g/cm3 |
Melting Point | >140°C (dec.) |
Boling Point | 413.5°C at 760 mmHg |
Flash Point | 203.9°C |
Solubility | Chloroform, Methanol (Slightly) |
Vapor Presure | 4.79E-07mmHg at 25°C |
Appearance | Solid |
Color | Light Beige to Beige |
Storage Condition | 2-8°C |
Refractive Index | 1.639 |
Methyl 3-cyano-1H-indole-4-carboxylate - Introduction
Methyl 3-cyanoindole-4-carboxylate is an organic compound. The following is a description of its nature, use, formulation and safety information:
Nature:
-Appearance: Colorless or light yellow crystal
-Molecular formula: C12H9NO2
-Molecular Weight: 199.21
-melting point: 90-93 ℃
-Boiling point: 338.2 ℃
-Solubility: Slightly soluble in water, soluble in organic solvents such as methanol and dimethyl sulfite
-Chemical reaction: The compound can be hydrolyzed to indolone and carbon dioxide under acidic conditions.
Use:
- Methyl 3-cyanoindole-4-carboxylate is an important organic synthesis intermediate, commonly used in the preparation of indole compounds.
-It can be used as a starting material for drug synthesis, and also for the synthesis of pesticides and dyes.
Method:
- Methyl 3-cyanoindole-4-carboxylate can be prepared by reacting indole with methyl cyanoformate. The specific preparation method may be reacting indole with methyl cyanoformate under alkaline conditions to generate the target product.
Safety Information:
- Methyl 3-cyanoindole-4-carboxylate has no clear hazard report under normal use conditions.
-When performing laboratory procedures, follow general chemical laboratory safety procedures and wear appropriate personal protective equipment, such as laboratory gloves and goggles.
-During storage and transportation, it should be kept in a dry, well-ventilated place, away from fire and oxidizing agents.
Last Update:2024-04-09 02:00:49